STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UGGT1UDP-glucose glycoprotein glucosyltransferase 1. (1333 aa)    
Predicted Functional Partners:
UGGT2
UDP-glucose glycoprotein glucosyltransferase 2.
  
  
 
0.902
OR52W1
Olfactory receptor family 52 subfamily W member 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.790
MED13
Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
  
 0.784
CANX
Calnexin.
   
 
 0.780
CALR
Calreticulin.
   
 
 0.756
PID1
Phosphotyrosine interaction domain containing 1.
      
 0.753
SELENOF
Selenoprotein F.
    
 
 0.718
KDELR3
ER lumen protein-retaining receptor.
    
 
 0.714
KLHL30
Kelch like family member 30.
      
 0.713
CATSPER3
Cation channel sperm associated 3.
   
  
 0.702
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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