STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GTSF1Gametocyte specific factor 1. (167 aa)    
Predicted Functional Partners:
HENMT1
HEN methyltransferase 1.
      
 0.834
ZGLP1
Zinc finger GATA like protein 1.
      
 0.725
TBPL2
TATA-box binding protein like 2.
      
 0.725
GUCA2B
Guanylate cyclase activator 2B.
      
 0.696
MOV10L1
Mov10 like RISC complex RNA helicase 1.
      
 0.685
SERPINI2
Serpin family I member 2; Belongs to the serpin family.
   
  
 0.635
ARFGEF3
ARFGEF family member 3.
      
 0.632
SGO2
Shugoshin 2.
      
 0.613
MED9
Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.612
PIWIL3
Piwi like RNA-mediated gene silencing 3; Belongs to the argonaute family.
   
 
 0.610
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.