LOC101102156 protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC101102156

Galectin. (355 aa)

Predicted Functional Partners:

TIGIT

0.795

CTLA4

0.743

CD44

0.725

LAG3

0.673

CD4

0.670

GALM

0.646

CD274

0.636

CLEC7A

0.620

LOC101111190

0.593

LOC101103965

0.593

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD274	CD4	ENSOARP00000014478	ENSOARP00000006749	CD274 molecule.	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	0.689
CD274	CD44	ENSOARP00000014478	ENSOARP00000020204	CD274 molecule.	CD44 molecule (Indian blood group).	0.599
CD274	CTLA4	ENSOARP00000014478	ENSOARP00000019665	CD274 molecule.	Cytotoxic T-lymphocyte-associated protein 4.	0.887
CD274	LAG3	ENSOARP00000014478	ENSOARP00000006987	CD274 molecule.	Lymphocyte activating 3.	0.710
CD274	LOC101102156	ENSOARP00000014478	ENSOARP00000017382	CD274 molecule.	Galectin.	0.636
CD274	LOC101111190	ENSOARP00000014478	ENSOARP00000011374	CD274 molecule.	Ig-like domain-containing protein.	0.430
CD274	TIGIT	ENSOARP00000014478	ENSOARP00000021068	CD274 molecule.	T cell immunoreceptor with Ig and ITIM domains.	0.698
CD4	CD274	ENSOARP00000006749	ENSOARP00000014478	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	CD274 molecule.	0.689
CD4	CD44	ENSOARP00000006749	ENSOARP00000020204	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	CD44 molecule (Indian blood group).	0.973
CD4	CTLA4	ENSOARP00000006749	ENSOARP00000019665	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	Cytotoxic T-lymphocyte-associated protein 4.	0.978
CD4	LAG3	ENSOARP00000006749	ENSOARP00000006987	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	Lymphocyte activating 3.	0.954
CD4	LOC101102156	ENSOARP00000006749	ENSOARP00000017382	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	Galectin.	0.670
CD4	LOC101111190	ENSOARP00000006749	ENSOARP00000011374	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	Ig-like domain-containing protein.	0.429
CD4	TIGIT	ENSOARP00000006749	ENSOARP00000021068	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	T cell immunoreceptor with Ig and ITIM domains.	0.884
CD44	CD274	ENSOARP00000020204	ENSOARP00000014478	CD44 molecule (Indian blood group).	CD274 molecule.	0.599
CD44	CD4	ENSOARP00000020204	ENSOARP00000006749	CD44 molecule (Indian blood group).	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	0.973
CD44	CTLA4	ENSOARP00000020204	ENSOARP00000019665	CD44 molecule (Indian blood group).	Cytotoxic T-lymphocyte-associated protein 4.	0.702
CD44	LAG3	ENSOARP00000020204	ENSOARP00000006987	CD44 molecule (Indian blood group).	Lymphocyte activating 3.	0.556
CD44	LOC101102156	ENSOARP00000020204	ENSOARP00000017382	CD44 molecule (Indian blood group).	Galectin.	0.725
CD44	TIGIT	ENSOARP00000020204	ENSOARP00000021068	CD44 molecule (Indian blood group).	T cell immunoreceptor with Ig and ITIM domains.	0.574