STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N4BP1NEDD4 binding protein 1. (838 aa)    
Predicted Functional Partners:
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
  0.922
CASP8
Caspase 8; Belongs to the peptidase C14A family.
   
 
 0.842
RNF19B
RBR-type E3 ubiquitin transferase.
   
  
 0.818
SLC35A2
Solute carrier family 35 member A2.
      
 0.691
FAM117B
Family with sequence similarity 117 member B.
   
  
 0.670
USP25
Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family.
      
 0.656
NEDD4
E3 ubiquitin-protein ligase.
    
 
 0.644
FAM189B
Family with sequence similarity 189 member B.
      
 0.614
SEC62
SEC62 homolog, preprotein translocation factor.
      
 0.599
FAM189A1
Family with sequence similarity 189 member A1.
    
 
 0.588
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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