STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR41WD repeat domain 41. (459 aa)    
Predicted Functional Partners:
SMCR8
SMCR8-C9orf72 complex subunit.
    
 0.998
C9orf72
C9orf72-SMCR8 complex subunit.
    
 0.992
RAB39B
RAB39B, member RAS oncogene family.
     
 0.961
RAB8A
RAB8A.
     
 0.959
RB1CC1
RB1 inducible coiled-coil 1.
    
 0.845
ATG101
Autophagy related 101.
    
 0.820
FNIP1
Folliculin interacting protein 1.
    
 
 0.755
ATG13
Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.
     
 0.736
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.711
CDC27
Cell division cycle 27.
   
 0.709
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.