STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRGPRFMAS related GPR family member F; Belongs to the G-protein coupled receptor 1 family. (341 aa)    
Predicted Functional Partners:
CNN1
Calponin-1; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
   
    0.795
EFEMP2
EGF containing fibulin extracellular matrix protein 2.
   
 
 0.749
FKBP10
Peptidylprolyl isomerase.
      
 0.747
COPZ2
Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
     
 0.735
PRRX2
Paired related homeobox 2.
    
 
 0.724
ZDHHC13
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.711
MAMDC2
MAM domain containing 2.
    
 
 0.710
VGLL3
Vestigial like family member 3.
      
 0.676
ATOH8
Atonal bHLH transcription factor 8.
      
 0.671
CALU
Calumenin.
      
 0.630
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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