STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (360 aa)    
Predicted Functional Partners:
S1PR2
Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.
     
 0.770
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
      
 0.750
HSD3B7
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family.
      
 0.746
GPR18
G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family.
   
 
0.652
CYP7B1
Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family.
      
 0.599
S1PR3
Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family.
     
 0.579
S1PR1
Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.576
GNAI2
Uncharacterized protein.
    
 
 0.557
CNR2
Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.549
CXCL13
SCY domain-containing protein.
      
 0.540
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.