STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NUDT6Nudix hydrolase 6; Belongs to the Nudix hydrolase family. (317 aa)    
Predicted Functional Partners:
RABL3
RAB, member of RAS oncogene family like 3.
      
 0.724
GTF2E1
General transcription factor IIE subunit 1.
      
 0.723
DPP10
Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family.
      
 0.627
NUDT5
Nudix hydrolase 5; Belongs to the Nudix hydrolase family.
      
 0.622
W5Q2Q8_SHEEP
Nudix hydrolase domain-containing protein.
      
 0.620
NUDT3
Nudix hydrolase 3.
      
 0.619
NUDT2
Nudix hydrolase 2; Belongs to the Nudix hydrolase family.
      
 0.617
NUDT22
Nudix hydrolase 22.
      
 0.616
NUDT18
Nudix hydrolase 18; Belongs to the Nudix hydrolase family.
      
 0.616
NUDT21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
      
 0.614
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.