STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOXD1Homeobox D1. (276 aa)    
Predicted Functional Partners:
IRX3
Iroquois homeobox 3.
   
 0.626
MTX2
Metaxin 2.
      
 0.590
PRRG1
Proline rich and Gla domain 1.
      
 0.539
EVX2
Even-skipped homeobox 2.
   
 
 0.509
GRM3
Glutamate metabotropic receptor 3.
      
 0.495
SPRY1
Sprouty RTK signaling antagonist 1.
    
 
 0.476
NIPAL2
NIPA like domain containing 2.
      
 0.472
PBX2
PBX homeobox 2.
    
 0.469
PBX4
PBX homeobox 4.
    
 0.469
PBX1
PBX homeobox 1.
    
 0.469
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.