STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (957 aa)    
Predicted Functional Partners:
GRIK2
Glutamate ionotropic receptor kainate type subunit 2.
  
 
0.863
GRIK3
Glutamate ionotropic receptor kainate type subunit 3.
  
 
0.804
GRIK1
Glutamate ionotropic receptor kainate type subunit 1.
  
 
0.795
TMEM8B
Transmembrane protein 8B.
      
 0.777
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.757
DLG3
Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.
   
 0.717
RNGTT
Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.
      
 0.691
AARS1
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.
      
 0.624
LOXL4
Lysyl oxidase like 4.
      
 0.614
CAMKV
CaM kinase like vesicle associated.
   
  
 0.604
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.