STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IKIK cytokine. (555 aa)    
Predicted Functional Partners:
SMU1
SMU1 DNA replication regulator and spliceosomal factor.
   
 0.998
PRPF6
Pre-mRNA processing factor 6.
   
 0.990
PRPF38A
Pre-mRNA processing factor 38A.
   
 0.986
MFAP1
Microfibril associated protein 1.
   
 0.986
WBP4
WW domain binding protein 4.
   
  0.968
TXNL4A
Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.
    
  0.967
ZMAT2
Zinc finger matrin-type 2.
    
  0.967
SRRM2
Serine/arginine repetitive matrix 2.
     
 0.941
SRRM1
Serine and arginine repetitive matrix 1.
   
 
  0.915
DDX5
DEAD-box helicase 5; Belongs to the DEAD box helicase family.
    
 0.914
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.