TLE3 protein (Ovis aries) - STRING interaction network

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Predicted Interactions

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Score

TLE3

TLE family member 3, transcriptional corepressor. (826 aa)

Predicted Functional Partners:

NRIP1

0.864

FOXA1

0.843

EP300

0.816

GATA3

0.802

PRDM16

0.658

LEF1

0.641

ESR1

0.609

NXPH3

0.604

TCF7L1

0.578

TCF7

0.566

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EP300	ESR1	ENSOARP00000019268	ENSOARP00000003565	E1A binding protein p300.	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	0.956
EP300	FOXA1	ENSOARP00000019268	ENSOARP00000008788	E1A binding protein p300.	Forkhead box A1.	0.924
EP300	GATA3	ENSOARP00000019268	ENSOARP00000014958	E1A binding protein p300.	GATA binding protein 3.	0.937
EP300	LEF1	ENSOARP00000019268	ENSOARP00000008654	E1A binding protein p300.	Lymphoid enhancer binding factor 1.	0.968
EP300	NRIP1	ENSOARP00000019268	ENSOARP00000001205	E1A binding protein p300.	Nuclear receptor interacting protein 1.	0.921
EP300	TCF7	ENSOARP00000019268	ENSOARP00000014760	E1A binding protein p300.	Transcription factor 7.	0.671
EP300	TCF7L1	ENSOARP00000019268	ENSOARP00000021981	E1A binding protein p300.	Transcription factor 7 like 1.	0.958
EP300	TLE3	ENSOARP00000019268	ENSOARP00000020073	E1A binding protein p300.	TLE family member 3, transcriptional corepressor.	0.816
ESR1	EP300	ENSOARP00000003565	ENSOARP00000019268	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	E1A binding protein p300.	0.956
ESR1	FOXA1	ENSOARP00000003565	ENSOARP00000008788	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	Forkhead box A1.	0.932
ESR1	GATA3	ENSOARP00000003565	ENSOARP00000014958	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	GATA binding protein 3.	0.878
ESR1	LEF1	ENSOARP00000003565	ENSOARP00000008654	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	Lymphoid enhancer binding factor 1.	0.460
ESR1	NRIP1	ENSOARP00000003565	ENSOARP00000001205	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	Nuclear receptor interacting protein 1.	0.909
ESR1	TLE3	ENSOARP00000003565	ENSOARP00000020073	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	TLE family member 3, transcriptional corepressor.	0.609
FOXA1	EP300	ENSOARP00000008788	ENSOARP00000019268	Forkhead box A1.	E1A binding protein p300.	0.924
FOXA1	ESR1	ENSOARP00000008788	ENSOARP00000003565	Forkhead box A1.	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	0.932
FOXA1	GATA3	ENSOARP00000008788	ENSOARP00000014958	Forkhead box A1.	GATA binding protein 3.	0.979
FOXA1	NRIP1	ENSOARP00000008788	ENSOARP00000001205	Forkhead box A1.	Nuclear receptor interacting protein 1.	0.920
FOXA1	TLE3	ENSOARP00000008788	ENSOARP00000020073	Forkhead box A1.	TLE family member 3, transcriptional corepressor.	0.843
GATA3	EP300	ENSOARP00000014958	ENSOARP00000019268	GATA binding protein 3.	E1A binding protein p300.	0.937