STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2109 aa)    
Predicted Functional Partners:
FIG4
FIG4 phosphoinositide 5-phosphatase.
    
 0.999
VAC14
VAC14 component of PIKFYVE complex.
    
 0.996
MTMR2
Myotubularin related protein 2.
     
 0.979
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
     
 0.967
PI4K2B
Phosphatidylinositol 4-kinase type 2 beta.
     
 0.948
PI4K2A
PI3K/PI4K domain-containing protein.
     
 0.939
PI4KB
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
     
 0.938
MTM1
Myotubularin 1.
     
 0.937
SACM1L
SAC1 like phosphatidylinositide phosphatase.
    
 0.933
MTMR1
Myotubularin related protein 1.
     
 0.927
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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