Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
COL8A2C1q domain-containing protein. (589 aa)    
Predicted Functional Partners:
COL8A1
Collagen type VIII alpha 1 chain.
  
0.940
SLC4A11
Solute carrier family 4 member 11.
      
 0.865
COL2A1
Collagen type II alpha 1 chain.
  
 
0.798
LOXHD1
Lipoxygenase homology domains 1.
    
 0.733
AGBL1
ATP/GTP binding protein like 1.
      
 0.733
COL14A1
Collagen type XIV alpha 1 chain.
  
 
0.679
KANK4
KN motif and ankyrin repeat domains 4.
    
 0.676
P4HA2
Prolyl 4-hydroxylase subunit alpha 2.
    
 0.674
C2CD2
C2 calcium dependent domain containing 2.
      
 0.667
ZEB1
Zinc finger E-box binding homeobox 1.
      
 0.642
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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