NFU1 protein (Ovis aries) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

NFU1

NFU1 iron-sulfur cluster scaffold. (254 aa)

Predicted Functional Partners:

NFS1

0.914

ISCU

0.903

SCLY

0.856

MOCOS

0.840

LOC780772

0.780

SDHB

0.779

NDUFS8

0.743

ISCA1

0.706

LOC101107943

0.706

ENSOARP00000021413

0.706

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOARP00000021413	ISCU	ENSOARP00000021413	ENSOARP00000019332	annotation not available	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.810
ENSOARP00000021413	MOCOS	ENSOARP00000021413	ENSOARP00000005832	annotation not available	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.495
ENSOARP00000021413	NDUFS8	ENSOARP00000021413	ENSOARP00000015462	annotation not available	NADH:ubiquinone oxidoreductase core subunit S8.	0.432
ENSOARP00000021413	NFS1	ENSOARP00000021413	ENSOARP00000015717	annotation not available	Aminotran_5 domain-containing protein.	0.747
ENSOARP00000021413	NFU1	ENSOARP00000021413	ENSOARP00000021269	annotation not available	NFU1 iron-sulfur cluster scaffold.	0.706
ENSOARP00000021413	SCLY	ENSOARP00000021413	ENSOARP00000020342	annotation not available	Selenocysteine lyase.	0.626
ISCA1	ISCU	ENSOARP00000009397	ENSOARP00000019332	Fe-S_biosyn domain-containing protein.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.810
ISCA1	MOCOS	ENSOARP00000009397	ENSOARP00000005832	Fe-S_biosyn domain-containing protein.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.495
ISCA1	NDUFS8	ENSOARP00000009397	ENSOARP00000015462	Fe-S_biosyn domain-containing protein.	NADH:ubiquinone oxidoreductase core subunit S8.	0.432
ISCA1	NFS1	ENSOARP00000009397	ENSOARP00000015717	Fe-S_biosyn domain-containing protein.	Aminotran_5 domain-containing protein.	0.747
ISCA1	NFU1	ENSOARP00000009397	ENSOARP00000021269	Fe-S_biosyn domain-containing protein.	NFU1 iron-sulfur cluster scaffold.	0.706
ISCA1	SCLY	ENSOARP00000009397	ENSOARP00000020342	Fe-S_biosyn domain-containing protein.	Selenocysteine lyase.	0.626
ISCU	ENSOARP00000021413	ENSOARP00000019332	ENSOARP00000021413	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	annotation not available	0.810
ISCU	ISCA1	ENSOARP00000019332	ENSOARP00000009397	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Fe-S_biosyn domain-containing protein.	0.810
ISCU	LOC101107943	ENSOARP00000019332	ENSOARP00000017066	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Fe-S_biosyn domain-containing protein.	0.810
ISCU	LOC780772	ENSOARP00000019332	ENSOARP00000014197	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.	0.420
ISCU	MOCOS	ENSOARP00000019332	ENSOARP00000005832	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.999
ISCU	NDUFS8	ENSOARP00000019332	ENSOARP00000015462	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	NADH:ubiquinone oxidoreductase core subunit S8.	0.652
ISCU	NFS1	ENSOARP00000019332	ENSOARP00000015717	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Aminotran_5 domain-containing protein.	0.999
ISCU	NFU1	ENSOARP00000019332	ENSOARP00000021269	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	NFU1 iron-sulfur cluster scaffold.	0.903