STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GUCA2BGuanylate cyclase activator 2B. (113 aa)    
Predicted Functional Partners:
GUCY2C
Guanylate cyclase.
   
 
 0.929
GUCA2A
Uncharacterized protein.
  
  
0.795
SLC46A2
Solute carrier family 46 member 2.
      
 0.785
FANCL
FA complementation group L.
      
 0.769
TMED3
Transmembrane p24 trafficking protein 3.
      
 0.697
GTSF1
Gametocyte specific factor 1.
      
 0.696
AQP4
Aquaporin-4 M1 isoform; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.665
PDZD3
PDZ domain containing 3.
   
  
 0.642
PRSS35
Serine protease 35.
      
 0.633
RAD18
RAD18 E3 ubiquitin protein ligase.
      
 0.621
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.