STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HJVHemojuvelin BMP co-receptor. (393 aa)    
Predicted Functional Partners:
TFR2
Transferrin receptor 2.
     
 0.942
HFE
Homeostatic iron regulator; Belongs to the MHC class I family.
     
 0.907
TMPRSS6
Transmembrane serine protease 6; Belongs to the peptidase S1 family.
    
 
 0.885
HAMP
Hepcidin.
      
 0.819
BMP6
Bone morphogenetic protein 6.
    
 
 0.792
BMP2
Bone morphogenetic protein 2.
    
 0.775
NEO1
Neogenin 1.
   
 0.759
GDF5
Growth differentiation factor 5.
    
 
 0.744
BMP4
TGF_BETA_2 domain-containing protein.
    
 
 0.663
TFRC
Transferrin receptor.
     
 0.651
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.