node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQP10 | AQP11 | ENSOARP00000002491 | ENSOARP00000007690 | Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | 0.960 |
AQP10 | AQP2 | ENSOARP00000002491 | ENSOARP00000019510 | Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | 0.877 |
AQP10 | AQP4 | ENSOARP00000002491 | ENSOARP00000007476 | Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin-4 M1 isoform; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.911 |
AQP10 | AQP5 | ENSOARP00000002491 | ENSOARP00000019504 | Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin-5; Forms a water-specific channel (By similarity). Plays an important role in fluid secretion in salivary glands. Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells. Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.936 |
AQP10 | AQP6 | ENSOARP00000002491 | ENSOARP00000019448 | Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.923 |
AQP10 | AQP7 | ENSOARP00000002491 | ENSOARP00000010151 | Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.537 |
AQP10 | AQP8 | ENSOARP00000002491 | ENSOARP00000019838 | Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.948 |
AQP10 | AQP9 | ENSOARP00000002491 | ENSOARP00000022418 | Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.687 |
AQP10 | MIP | ENSOARP00000002491 | ENSOARP00000009442 | Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Lens fiber major intrinsic protein; Water channel. Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core. Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (By similarity). Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.935 |
AQP11 | AQP10 | ENSOARP00000007690 | ENSOARP00000002491 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.960 |
AQP11 | AQP2 | ENSOARP00000007690 | ENSOARP00000019510 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | 0.889 |
AQP11 | AQP4 | ENSOARP00000007690 | ENSOARP00000007476 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin-4 M1 isoform; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.981 |
AQP11 | AQP5 | ENSOARP00000007690 | ENSOARP00000019504 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin-5; Forms a water-specific channel (By similarity). Plays an important role in fluid secretion in salivary glands. Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells. Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity); Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.914 |
AQP11 | AQP6 | ENSOARP00000007690 | ENSOARP00000019448 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.979 |
AQP11 | AQP7 | ENSOARP00000007690 | ENSOARP00000010151 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.982 |
AQP11 | AQP8 | ENSOARP00000007690 | ENSOARP00000019838 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.983 |
AQP11 | AQP9 | ENSOARP00000007690 | ENSOARP00000022418 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.946 |
AQP11 | LCN8 | ENSOARP00000007690 | ENSOARP00000001802 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Lipocalin 8; Belongs to the calycin superfamily. Lipocalin family. | 0.665 |
AQP11 | MIP | ENSOARP00000007690 | ENSOARP00000009442 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Lens fiber major intrinsic protein; Water channel. Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core. Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (By similarity). Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.887 |
AQP2 | AQP10 | ENSOARP00000019510 | ENSOARP00000002491 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.877 |