STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PYGO1Pygopus family PHD finger 1. (403 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.911
BCL9
BCL9 transcription coactivator.
    
 0.866
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.831
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.816
JUP
Junction plakoglobin.
   
 0.787
KMT2D
Lysine methyltransferase 2D.
   
 0.719
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.689
W5PK24_SHEEP
Uncharacterized protein.
    
  0.671
MEN1
Uncharacterized protein.
    
  0.671
LEF1
Lymphoid enhancer binding factor 1.
    
 0.647
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.