STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (314 aa)    
Predicted Functional Partners:
ETA81667.1
O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol.
 
 
 0.993
ETA81621.1
Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine.
 
 
 0.945
ETA79392.1
Homoserine dehydrogenase.
  
 
 0.911
ETA81535.1
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.882
ETA81533.1
Homocysteine methyltransferase.
  
  
 0.846
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
  0.841
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
  0.832
ETA79650.1
Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine.
   
 
 0.832
ETA79618.1
Serine dehydratase subunit alpha; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.827
ETA79619.1
Serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.827
Your Current Organism:
Youngiibacter fragilis
NCBI taxonomy Id: 994573
Other names: Clostridium sp. 232.1, Y. fragilis 232.1, Youngiibacter fragile 232.1, Youngiibacter fragilis 232.1
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