STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ETA79981.1Methionine synthase. (551 aa)    
Predicted Functional Partners:
ETA79431.1
D-ornithine aminomutase s component.
 
 
  0.864
ETA81533.1
Homocysteine methyltransferase.
  
 
 0.857
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
   
 0.845
ETA79066.1
NADP transhydrogenase subunit alpha; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
   
 0.812
ETA81066.1
mutL.
      0.673
ETA81535.1
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.668
ETA81667.1
O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol.
     
  0.640
luxS
S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
  0.640
gcvT
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
     
  0.640
ETA80993.1
Catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; Belongs to the AdoMet synthase family.
     
  0.600
Your Current Organism:
Youngiibacter fragilis
NCBI taxonomy Id: 994573
Other names: Clostridium sp. 232.1, Y. fragilis 232.1, Youngiibacter fragile 232.1, Youngiibacter fragilis 232.1
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