STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFT33407.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (404 aa)    
Predicted Functional Partners:
SFT85741.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.921
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.799
SFT85764.1
Methylenetetrahydrofolate reductase (NADPH); Belongs to the methylenetetrahydrofolate reductase family.
  
 0.725
SFT64265.1
S-adenosylmethionine synthetase.
  
 0.686
SFT96120.1
S-adenosylmethionine synthetase.
  
 0.686
SFT97026.1
S-adenosylmethionine synthetase.
  
 0.686
SFT55048.1
Homoserine dehydrogenase.
   
 
 0.681
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
   
 
 0.680
SFT83768.1
Cystathionine beta-synthase.
    
 0.660
SFT43625.1
Methionine-gamma-lyase.
  
 
 0.643
Your Current Organism:
Actinopolyspora righensis
NCBI taxonomy Id: 995060
Other names: A. righensis, Actinopolyspora righensis Meklat et al. 2014 emend. Nouioui et al. 2018, Actinopolyspora sp. H23, CCUG 63368, DSM 45501, MTCC 11562, strain H23
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