STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFT94055.1Dihydrofolate reductase. (185 aa)    
Predicted Functional Partners:
SFT85741.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.781
SFT34151.1
Dihydrofolate reductase.
  
     0.760
SFT35196.1
NAD(P)H-binding.
 
   
  0.631
SFT94067.1
Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains.
  
    0.628
SFT94061.1
L-amino acid N-acyltransferase YncA.
  
    0.612
SFT33356.1
Uncharacterized conserved protein YndB, AHSA1/START domain.
 
     0.563
SFT94074.1
TIGR00375 family protein.
       0.453
SFT61114.1
Dihydrofolate reductase.
  
     0.427
Your Current Organism:
Actinopolyspora righensis
NCBI taxonomy Id: 995060
Other names: A. righensis, Actinopolyspora righensis Meklat et al. 2014 emend. Nouioui et al. 2018, Actinopolyspora sp. H23, CCUG 63368, DSM 45501, MTCC 11562, strain H23
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.