node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDQ88702.1 | SDQ88730.1 | SAMN04489718_2564 | SAMN04489718_2565 | UTP--glucose-1-phosphate uridylyltransferase. | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.650 |
SDQ88702.1 | SDQ88758.1 | SAMN04489718_2564 | SAMN04489718_2566 | UTP--glucose-1-phosphate uridylyltransferase. | Putative regulatory protein, FmdB family. | 0.462 |
SDQ88730.1 | SDQ88702.1 | SAMN04489718_2565 | SAMN04489718_2564 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | UTP--glucose-1-phosphate uridylyltransferase. | 0.650 |
SDQ88730.1 | SDQ88758.1 | SAMN04489718_2565 | SAMN04489718_2566 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Putative regulatory protein, FmdB family. | 0.541 |
SDQ88730.1 | SDR02256.1 | SAMN04489718_2565 | SAMN04489718_3130 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Membrane associated serine protease, rhomboid family. | 0.527 |
SDQ88730.1 | SDR11522.1 | SAMN04489718_2565 | SAMN04489718_3598 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | NADH dehydrogenase subunit E. | 0.531 |
SDQ88730.1 | fhs | SAMN04489718_2565 | SAMN04489718_1595 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.767 |
SDQ88730.1 | fmt | SAMN04489718_2565 | SAMN04489718_0267 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.606 |
SDQ88730.1 | folD | SAMN04489718_2565 | SAMN04489718_3813 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.853 |
SDQ88730.1 | glyA | SAMN04489718_2565 | SAMN04489718_1644 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.712 |
SDQ88730.1 | pheT | SAMN04489718_2565 | SAMN04489718_1380 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.713 |
SDQ88730.1 | purN | SAMN04489718_2565 | SAMN04489718_3807 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate; Belongs to the GART family. | 0.580 |
SDQ88758.1 | SDQ88702.1 | SAMN04489718_2566 | SAMN04489718_2564 | Putative regulatory protein, FmdB family. | UTP--glucose-1-phosphate uridylyltransferase. | 0.462 |
SDQ88758.1 | SDQ88730.1 | SAMN04489718_2566 | SAMN04489718_2565 | Putative regulatory protein, FmdB family. | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.541 |
SDR02256.1 | SDQ88730.1 | SAMN04489718_3130 | SAMN04489718_2565 | Membrane associated serine protease, rhomboid family. | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.527 |
SDR11522.1 | SDQ88730.1 | SAMN04489718_3598 | SAMN04489718_2565 | NADH dehydrogenase subunit E. | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.531 |
fhs | SDQ88730.1 | SAMN04489718_1595 | SAMN04489718_2565 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.767 |
fhs | fmt | SAMN04489718_1595 | SAMN04489718_0267 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.655 |
fhs | folD | SAMN04489718_1595 | SAMN04489718_3813 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.989 |
fhs | glyA | SAMN04489718_1595 | SAMN04489718_1644 | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.945 |