STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY30516.1DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (387 aa)    
Predicted Functional Partners:
AFY31921.1
TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ana:all4705 DNA polymerase III subunit delta'; SPTR: All4705 protein; TIGRFAM: DNA polymerase III, delta prime subunit.
 
 0.999
AFY32371.1
DNA polymerase I; PFAM: 3'-5' exonuclease; 5'-3' exonuclease, C-terminal SAM fold; DNA polymerase family A; 5'-3' exonuclease, N-terminal resolvase-like domain; TIGRFAM: DNA polymerase I; COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR018320:IPR020046:IPR020047:IPR002562:IPR 001098:IPR002421:IPR008918; KEGG: ana:alr1254 DNA polymerase I; PFAM: DNA-directed DNA polymerase, family A, palm domain; 5'-3' exonuclease, alpha-helical arch, N-terminal; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; SMART: 5'-3' exonuclease, N-terminal; Helix-hairp [...]
 
 0.999
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 0.998
AFY31880.1
AAA ATPase central domain protein; PFAM: DNA polymerase III subunits gamma and tau domain III; Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: DNA polymerase III, subunit gamma and tau; intein N-terminal splicing region; intein C-terminal splicing region; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterProIPR003959:IPR010372:IPR003593:IPR003587:IPR 003586:IPR006141; KEGG: syn:sll1360 DNA polymerase III subunit; PFAM: ATPase, AAA-type, core; DNA polymerase III, delta; SMART: Hedgehog/intein hint, N-terminal; ATPase, AAA+ type, core; Hedgehog/intein hint domain, C-term [...]
   
 0.998
AFY34560.1
PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790:IPR010372; KEGG: npu:Npun_F4117 DNA polymerase III subunit delta; PFAM: DNA polymerase III, delta; SPTR: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
 
 
 0.998
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
  
 0.997
AFY31018.1
PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; TIGRFAM: intein N-terminal splicing region; DNA-directed DNA polymerase III (polc); COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013:IPR011708:IPR003141:IPR003587:IPR 004805:IPR006141; KEGG: ava:Ava_1603 DNA polymerase III subunit alpha; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; Hedgehog/intein hint, N-terminal; SPTR: Intein; TIGRFAM: DNA polymerase III, alpha subunit; Intein splice site.
  
 
 0.992
AFY34439.1
PFAM: OB-fold nucleic acid binding domain; TIGRFAM: intein C-terminal splicing region; COGs: COG0587 DNA polymerase III alpha subunit; InterPro IPR006141:IPR004365; KEGG: npu:Npun_F5684 DNA polymerase III subunit alpha; PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: Nucleic acid binding, OB-fold, tRNA/helicase-type.
  
 
 0.992
rnhB
RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
 
 0.947
AFY33660.1
Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth); COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: ava:Ava_2559 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: Exodeoxyribonuclease III; SPTR: Exodeoxyribonuclease III xth; TIGRFAM: AP endonuclease, family 1; Exodeoxyribonuclease III xth.
   
 0.928
Your Current Organism:
Calothrix sp. PCC7507
NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507
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