STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY30562.1Diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160:IPR013656:IPR000014; KEGG: npu:Npun_R5220 diguanylate cyclase with PAS/PAC sensor; PFAM: Diguanylate cyclase, predicted; PAS fold-4; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: Diguanylate cyclase, predicted; PAS. (547 aa)    
Predicted Functional Partners:
AFY30750.1
GAF sensor hybrid histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003018:IPR003661:IPR003594:IPR 001789; KEGG: npu:Npun_F2686 GAF sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-bind [...]
  
 
 0.983
AFY35616.1
PFAM: EAL domain; Response regulator receiver domain; COGs: COG2200 FOG: EAL domain; InterPro IPR001789:IPR001633; KEGG: npu:Npun_R4503 response regulator receiver modulated diguanylate phosphodiesterase; PFAM: Diguanylate phosphodiesterase, EAL domain; Signal transduction response regulator, receiver domain; SMART: Diguanylate phosphodiesterase, EAL domain; Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver modulated diguanylate phosphodiesterase.
 
 0.981
AFY34690.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR013656:IPR013655; KEGG: npu:Npun_F2908 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS [...]
  
 
 0.965
AFY30917.1
PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; CHASE3 domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR007891:IPR013656:IPR003661:IPR 003594:IPR001789:IPR008207:IPR000014:IPR001610; KEGG: ava:Ava_1564 multi-sensor hybrid histidine kinase; PFAM: CHASE3; GAF; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; Signal transductio [...]
 
 0.957
AFY35328.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 013655:IPR003661:IPR003594:IPR000014:IPR001610; KEGG: ana:all0729 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; PAS fold; GAF; PAS fold-4; PAS fold-3; Signal transduction histidine kinase, subgroup 1, dimeris [...]
 
 
 0.947
AFY35147.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054:IPR019278; KEGG: npu:Npun_R0896 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; GAF; Domain of unknown function DUF2308, sensory; Signal transducti [...]
  
 
 0.942
AFY35138.1
Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: HD domain; Response regulator receiver domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789:IPR003607:IPR006674; KEGG: npu:Npun_F0906 response regulator receiver modulated metal dependent phosphohydrolase; PFAM: Signal transduction response regulator, receiver domain; Metal-dependent phosphohydrolase, HD subdomain; SMART: Signal transduction response regulator, receiver domain; Metal-dependent phosphohydrolase, HD domain; SPTR: Response regul [...]
 
 0.920
AFY31205.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003661:IPR003594; KEGG: naz:Aazo_0932 response regulator receiver sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: Signal transduction response regulator, receiver domain; Signal transduction hi [...]
 
 
 0.915
AFY34285.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR003661:IPR003594:IPR 013767; KEGG: npu:Npun_R2901 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold; SMART: ATPase [...]
 
 
 0.913
AFY35468.1
PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160:IPR001633; KEGG: npu:Npun_R5282 diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase/phosphodiesterase; TIGRFAM: Diguanylate cyclase, predicted.
 
 0.902
Your Current Organism:
Calothrix sp. PCC7507
NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507
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