STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY30654.1PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: npu:Npun_R0360 hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation HypD protein; SPTR: Hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein. (392 aa)    
Predicted Functional Partners:
AFY30653.1
PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF; COGs: COG0298 Hydrogenase maturation factor; InterPro IPR001109; KEGG: ava:Ava_4603 hydrogenase expression/formation protein (HUPF/HYPC); PFAM: Hydrogenase expression/formation protein, HupF/HypC; SPTR: Hydrogenase expression/formation protein; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC.
 
 
 0.999
AFY30657.1
Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR000728:IPR010918:IPR011854; KEGG: npu:Npun_R0359 hydrogenase expression/formation protein HypE; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; SPTR: Hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE.
 
 
 0.999
AFY30659.1
Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR003495:IPR004392; KEGG: ana:alr0700 hydrogenase expression/formation protein; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase expression/formation protein; TIGRFAM: Hydrogenase accessory protein HypB.
 
  
 0.969
AFY30652.1
(NiFe) hydrogenase maturation protein HypF; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; COGs: COG0068 Hydrogenase maturation factor; InterPro IPR001792:IPR011125:IPR006070:IPR004421; KEGG: npu:Npun_R0362 (NiFe) hydrogenase maturation protein HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type; SPTR: (NiFe) hydrogenase maturation protein HypF; TIGRFAM: Carbamoyltransferase, HypF-type.
 
  
 0.943
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.882
AFY30645.1
PFAM: Nickel-dependent hydrogenase; COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501; KEGG: npu:Npun_F0369 nickel-dependent hydrogenase, large subunit, HupL; PFAM: Nickel-dependent hydrogenase, large subunit; PRIAM: Cytochrome-c3 hydrogenase; SPTR: Uptake hydrogenase large subunit.
 
 
 0.870
AFY30646.1
Hydrogenase (acceptor); PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA); COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR006137; KEGG: npu:Npun_F0368 Ni Fe-hydrogenase I small subunit, HupS; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: Hydrogenase (acceptor); SPTR: Uptake hydrogenase small subunit.
 
  
 0.832
hypA-2
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.786
AFY30655.1
PFAM: Tautomerase enzyme; TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; COGs: COG1942 Uncharacterized protein 4-oxalocrotonate tautomerase homolog; InterPro IPR004370:IPR018191; KEGG: ava:Ava_4605 4-oxalocrotonate tautomerase; PFAM: 4-oxalocrotonate tautomerase; SPTR: Putative uncharacterized protein; TIGRFAM: 4-oxalocrotonate tautomerase, bacteria/archaea.
       0.682
AFY30634.1
PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease; COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: npu:Npun_F0374 hydrogenase maturation protease; PFAM: Peptidase A31, hydrogen uptake protein; SPTR: Hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogen uptake protein.
 
   
 0.533
Your Current Organism:
Calothrix sp. PCC7507
NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507
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