STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AFY30950.1Thioesterase superfamily protein; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis; Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily. (148 aa)    
Predicted Functional Partners:
menB
1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
  
  
 0.922
AFY33175.1
6-deoxyerythronolide-B synthase; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR020841:IPR020801:IPR020842:IPR020806:IPR 014030:IPR014031:IPR014043:IPR013968:IPR006163; KEGG: amr:AM1_A0228 beta-ketoacyl synthase, putative; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; Acyl transferase; Polyketide synthase, KR; Phosphopantetheine-binding; PRIAM: 6-deoxyerythronolide-B [...]
  
 
 0.822
AFY35882.1
Polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR004432:IPR014030:IPR014031:IPR014043:IPR 020841:IPR020801; KEGG: ava:Ava_2590 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; Acyl transferase; PRIAM: 6-deoxyerythronolide-B synthase; SM [...]
  
 
 0.822
AFY30949.1
PFAM: Protein of unknown function (DUF820); InterPro IPR008538; KEGG: cyc:PCC7424_3403 protein of unknown function DUF820; PFAM: Domain of unknown function DUF820; SPTR: Putative uncharacterized protein.
       0.661
AFY33667.1
PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410:IPR020801; KEGG: npu:Npun_F0100 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SMART: Polyketide synthase, acyl transferase domain; SPTR: Malonyl coenzyme A-acyl carrier protein transacylase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase.
  
 
 0.514
AFY30948.1
KEGG: npu:Npun_F2706 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.481
AFY35915.1
KEGG: npu:Npun_R1718 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.477
menA
1,4-dihydroxy-2-naphthoate phytyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily.
 
   
 0.431
menD
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
  
   
 0.425
AFY33178.1
PFAM: Acyl transferase domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR020841:IPR020801:IPR014030:IPR014031:IPR 014043; KEGG: npu:Npun_R3430 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; Acyl transferase; PRIAM: 6-deoxyerythronolide-B synthase; SMART: Polyketide synthase, beta-ketoacyl synthase domain; Polyketide synthase, acyl transferase domain; SPTR: Beta-ketoacyl synthase.
   
 
 0.408
Your Current Organism:
Calothrix sp. PCC7507
NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507
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