STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY31431.1PFAM: Response regulator receiver domain; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001789:IPR001932:IPR010822; KEGG: ana:all3759 two-component response regulator; PFAM: Sporulation stage II, protein E C-terminal; Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; Protein phosphatase 2C-like; SPTR: Two-component response regulator. (396 aa)    
Predicted Functional Partners:
AFY31432.1
COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); KEGG: npu:Npun_F1684 putative anti-sigma regulatory factor, serine/threonine protein kinase; SPTR: Putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.930
AFY30917.1
PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; CHASE3 domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR007891:IPR013656:IPR003661:IPR 003594:IPR001789:IPR008207:IPR000014:IPR001610; KEGG: ava:Ava_1564 multi-sensor hybrid histidine kinase; PFAM: CHASE3; GAF; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; Signal transductio [...]
 
  
0.886
AFY31433.1
Hpt sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Hpt domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR001789:IPR008207; KEGG: npu:Npun_R1685 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; SPTR: Multi-sensor hybrid histidi [...]
  
0.790
AFY35273.1
Multi-component transcriptional regulator, winged helix family; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Transcriptional regulatory protein, C terminal; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789:IPR001867:IPR000014:IPR003661:IPR 003594:IPR008207:IPR013767:IPR013955; KEGG: ana:alr2428 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-bind [...]
 
  
0.762
AFY36408.1
PFAM: Heme NO binding; InterPro IPR011644; KEGG: npu:Npun_R4836 heme NO binding domain-containing protein; PFAM: Haem NO binding; SPTR: Heme NO binding domain protein.
  
    0.757
AFY34192.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: ava:Ava_4580 anti-sigma-factor antagonist domain-containing protein; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
 
 
 0.722
AFY36191.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: ava:Ava_3722 anti-sigma-factor antagonist domain-containing protein; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
 
 
 0.719
AFY31430.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: npu:Npun_F1682 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
 
 
 0.717
AFY31204.1
PFAM: Response regulator receiver domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789; KEGG: npu:Npun_F1447 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver protein.
  
    0.690
AFY33354.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645:IPR003658; KEGG: npu:Npun_R3892 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
 
 
 0.686
Your Current Organism:
Calothrix sp. PCC7507
NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507
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