AFY31608.1 protein (Calothrix sp. PCC7507) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

AFY31608.1

KEGG: cyh:Cyan8802_4269 hypothetical protein; SPTR: Genome sequencing data, contig C298. (272 aa)

Predicted Functional Partners:

AFY31609.1

0.775

AFY31610.1

0.773

AFY31599.1

0.506

AFY31600.1

0.506

AFY31601.1

0.506

AFY31602.1

0.506

AFY31603.1

0.506

AFY31604.1

0.506

AFY31605.1

0.506

AFY31606.1

0.506

Your Current Organism:

Calothrix sp. PCC7507

NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFY31599.1	AFY31600.1	Cal7507_1125	Cal7507_1126	KEGG: npu:Npun_F1676 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: ava:Ava_D0001 hypothetical protein; SPTR: Putative uncharacterized protein.	0.773
AFY31599.1	AFY31601.1	Cal7507_1125	Cal7507_1127	KEGG: npu:Npun_F1676 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: tit:Thit_1376 hypothetical protein; SPTR: Putative uncharacterized protein.	0.773
AFY31599.1	AFY31602.1	Cal7507_1125	Cal7507_1128	KEGG: npu:Npun_F1676 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: mca:MCA2906 hypothetical protein; SPTR: Putative uncharacterized protein.	0.773
AFY31599.1	AFY31603.1	Cal7507_1125	Cal7507_1129	KEGG: npu:Npun_F1676 hypothetical protein; SPTR: Putative uncharacterized protein.	Hypothetical protein.	0.773
AFY31599.1	AFY31604.1	Cal7507_1125	Cal7507_1130	KEGG: npu:Npun_F1676 hypothetical protein; SPTR: Putative uncharacterized protein.	Hypothetical protein.	0.773
AFY31599.1	AFY31605.1	Cal7507_1125	Cal7507_1131	KEGG: npu:Npun_F1676 hypothetical protein; SPTR: Putative uncharacterized protein.	Hypothetical protein.	0.773
AFY31599.1	AFY31606.1	Cal7507_1125	Cal7507_1132	KEGG: npu:Npun_F1676 hypothetical protein; SPTR: Putative uncharacterized protein.	Hypothetical protein.	0.773
AFY31599.1	AFY31608.1	Cal7507_1125	Cal7507_1134	KEGG: npu:Npun_F1676 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: cyh:Cyan8802_4269 hypothetical protein; SPTR: Genome sequencing data, contig C298.	0.506
AFY31599.1	AFY31609.1	Cal7507_1125	Cal7507_1135	KEGG: npu:Npun_F1676 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: cyj:Cyan7822_4519 hypothetical protein; SPTR: Putative uncharacterized protein.	0.506
AFY31599.1	AFY31610.1	Cal7507_1125	Cal7507_1136	KEGG: npu:Npun_F1676 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: cyj:Cyan7822_0656 glucose-6-phosphatedehydrogenase-6- phosphogluconolactonase; SPTR:Glucose-6-phosphatedehydrogenase-6-phosphogluc onolactonase.	0.506
AFY31600.1	AFY31599.1	Cal7507_1126	Cal7507_1125	KEGG: ava:Ava_D0001 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: npu:Npun_F1676 hypothetical protein; SPTR: Putative uncharacterized protein.	0.773
AFY31600.1	AFY31601.1	Cal7507_1126	Cal7507_1127	KEGG: ava:Ava_D0001 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: tit:Thit_1376 hypothetical protein; SPTR: Putative uncharacterized protein.	0.773
AFY31600.1	AFY31602.1	Cal7507_1126	Cal7507_1128	KEGG: ava:Ava_D0001 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: mca:MCA2906 hypothetical protein; SPTR: Putative uncharacterized protein.	0.773
AFY31600.1	AFY31603.1	Cal7507_1126	Cal7507_1129	KEGG: ava:Ava_D0001 hypothetical protein; SPTR: Putative uncharacterized protein.	Hypothetical protein.	0.773
AFY31600.1	AFY31604.1	Cal7507_1126	Cal7507_1130	KEGG: ava:Ava_D0001 hypothetical protein; SPTR: Putative uncharacterized protein.	Hypothetical protein.	0.773
AFY31600.1	AFY31605.1	Cal7507_1126	Cal7507_1131	KEGG: ava:Ava_D0001 hypothetical protein; SPTR: Putative uncharacterized protein.	Hypothetical protein.	0.773
AFY31600.1	AFY31606.1	Cal7507_1126	Cal7507_1132	KEGG: ava:Ava_D0001 hypothetical protein; SPTR: Putative uncharacterized protein.	Hypothetical protein.	0.773
AFY31600.1	AFY31608.1	Cal7507_1126	Cal7507_1134	KEGG: ava:Ava_D0001 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: cyh:Cyan8802_4269 hypothetical protein; SPTR: Genome sequencing data, contig C298.	0.506
AFY31600.1	AFY31609.1	Cal7507_1126	Cal7507_1135	KEGG: ava:Ava_D0001 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: cyj:Cyan7822_4519 hypothetical protein; SPTR: Putative uncharacterized protein.	0.506
AFY31600.1	AFY31610.1	Cal7507_1126	Cal7507_1136	KEGG: ava:Ava_D0001 hypothetical protein; SPTR: Putative uncharacterized protein.	KEGG: cyj:Cyan7822_0656 glucose-6-phosphatedehydrogenase-6- phosphogluconolactonase; SPTR:Glucose-6-phosphatedehydrogenase-6-phosphogluc onolactonase.	0.506

page 1 of 6

Network Stats

number of nodes:

3

number of edges:

2

average node degree:

1.33

avg. local clustering coefficient:

0.667

expected number of edges:

2

PPI enrichment p-value:

0.531

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0098660

Inorganic ion transmembrane transport

5 of 75

1.48

1.64

4.67e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

4 of 9

2.3

2.78

3.71e-06

GO:0005216

Ion channel activity

5 of 29

1.89

2.47

3.71e-06

GO:0015075

Ion transmembrane transporter activity

6 of 106

1.41

1.76

5.17e-06

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

2 of 2

2.65

1.52

0.0017

GO:0022853

Active ion transmembrane transporter activity

3 of 37

1.56

1.14

0.0032

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016469

Proton-transporting two-sector ATPase complex

5 of 11

2.31

3.91

1.31e-08

GO:0045259

Proton-transporting ATP synthase complex

4 of 10

2.26

3.01

1.06e-06

GO:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

3 of 5

2.43

2.48e-05

GO:0033177

Proton-transporting two-sector ATPase complex, proton-transporting domain

2 of 6

2.18

1.47

0.0016

GO:0031676

Plasma membrane-derived thylakoid membrane

4 of 98

1.27

1.07

0.0012

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1356

ATP synthesis, and Adenylate kinase activity

4 of 12

2.18

2.34

2.39e-05

CL:1360

ATP synthesis

3 of 7

2.29

1.75

0.00049

CL:3455

Mixed, incl. Cation/H+ exchanger, and Potassium ion transport

3 of 24

1.75

1.05

0.0078

CL:3493

MgtC family, and Cation transporter/ATPase, N-terminus

2 of 5

2.26

1.04

0.0119

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

6 of 71

1.58

2.26

6.23e-07

map00195

Photosynthesis

4 of 58

1.49

1.39

0.00043

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016469

Proton-transporting two-sector ATPase complex

5 of 12

2.27

3.69

3.28e-08

GOCC:0045259

Proton-transporting ATP synthase complex

4 of 11

2.22

2.81

2.57e-06

GOCC:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

3 of 5

2.43

2.31

4.39e-05

GOCC:0033177

Proton-transporting two-sector ATPase complex, proton-transporting domain

2 of 7

2.11

1.12

0.0078

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0066

ATP synthesis

4 of 9

2.3

2.9

2.12e-06

KW-0375

Hydrogen ion transport

4 of 10

2.26

2.87

2.12e-06

KW-0139

CF(1)

3 of 5

2.43

2.36

3.45e-05

KW-0793

Thylakoid

4 of 79

1.36

1.17

0.0010

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02874

ATP synthase alpha/beta family, beta-barrel domain

2 of 2

2.65

0.96

0.0181

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036121

ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily

2 of 2

2.65

0.74

0.0456

IPR020003

ATPase, alpha/beta subunit, nucleotide-binding domain, active site

2 of 2

2.65

0.74

0.0456

IPR004100

ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain

2 of 2

2.65

0.74

0.0456

IPR000194

ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain

2 of 2

2.65

0.74

0.0456

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