STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY32071.1PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit; COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: ava:Ava_1416 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Lumazine-binding protein; TIGRFAM: Lumazine-binding protein. (229 aa)    
Predicted Functional Partners:
AFY31355.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.999
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.999
AFY35539.1
PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; COGs: COG0117 Pyrimidine deaminase; InterPro IPR002125; KEGG: npu:Npun_F1498 CMP/dCMP deaminase, zinc-binding; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: CMP/dCMP deaminase, zinc-binding.
 
  
 0.953
AFY33152.1
Riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; COGs: COG0196 FAD synthase; InterPro IPR015865:IPR002606:IPR015864; KEGG: npu:Npun_F0943 bifunctional riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; manually curated; Belongs to the ribF family.
 
 
 0.944
AFY35561.1
PFAM: GTP cyclohydrolase N terminal; GTP cyclohydrolase II; COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: cyb:CYB_0230 hypothetical protein; PFAM: GTP cyclohydrolase II, RibA; SPTR: GTP cyclohydrolase-2.
 
 
 0.890
AFY33832.1
Bifunctional deaminase-reductase domain protein; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; COGs: COG1985 Pyrimidine reductase riboflavin biosynthesis; InterPro IPR002734; KEGG: npu:Npun_F1237 deaminase-reductase domain-containing protein; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; SPTR: Bifunctional deaminase-reductase domain protein.
 
  
 0.883
hisI
PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphohydrolase; Histidine biosynthesis bifunctional protein HisIE; InterPro IPR002496:IPR021130:IPR008179:IPR023019; KEGG: npu:Npun_F4098 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; PRIAM: Phosphoribosyl-AMP cyclohydrolase., Phosphoribosyl-ATP d [...]
  
    0.810
AFY35560.1
PFAM: Protein of unknown function (DUF1688); InterPro IPR012469; KEGG: sno:Snov_0100 protein of unknown function DUF1688; PFAM: Protein of unknown function DUF1688; SPTR: Putative uncharacterized protein.
  
 
 0.795
rpmE
LSU ribosomal protein L31P; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
   
    0.723
Your Current Organism:
Calothrix sp. PCC7507
NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507
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