STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AFY32600.1Geranylgeranyl reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: geranylgeranyl reductase family; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR011777:IPR006076; KEGG: naz:Aazo_0064 geranylgeranyl reductase; PFAM: FAD dependent oxidoreductase; SPTR: Geranylgeranyl reductase; TIGRFAM: Geranylgeranyl reductase, plant/prokaryotic. (373 aa)    
Predicted Functional Partners:
AFY35584.1
Chlorophyll synthase; PFAM: UbiA prenyltransferase family; TIGRFAM: bacteriochlorophyll/chlorophyll synthetase; chlorophyll synthase, ChlG; COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR011799:IPR006372; KEGG: ana:all4480 bacteriochlorophyll/chlorophyll a synthase; PFAM: UbiA prenyltransferase; PRIAM: Chlorophyll synthase; SPTR: Chlorophyll synthase 33 kD subunit; TIGRFAM: Chlorophyll synthase, ChlG; Bacteriochlorophyll/chlorophyll synthetase.
 
  
 0.723
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
      
 0.693
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
     
 0.687
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
  
  
 0.686
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
      
 0.680
AFY30807.1
Squalene-hopene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase; COGs: COG1657 Squalene cyclase; InterPro IPR001330:IPR006400:IPR018333; KEGG: npu:Npun_R6245 squalene/oxidosqualene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene/oxidosqualene cyclase; TIGRFAM: Hopene cyclase; Squalene cyclase.
      
 0.678
AFY36234.1
Protoporphyrin IX magnesium-chelatase; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
 
  
 0.650
AFY30904.1
Geranylgeranyl reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: geranylgeranyl reductase; geranylgeranyl reductase family; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR002938:IPR010253:IPR011774:IPR011777; KEGG: ava:Ava_1497 geranylgeranyl reductase; PFAM: Monooxygenase, FAD-binding; SPTR: Geranylgeranyl hydrogenase; TIGRFAM: Geranylgeranyl reductase, plant/cyanobacteria; Geranylgeranyl reductase; Geranylgeranyl reductase, plant/prokaryotic.
  
  
 
0.644
AFY35082.1
Cobaltochelatase CobN subunit; PFAM: Domain of unknown function (DUF3479); CobN/Magnesium Chelatase; TIGRFAM: magnesium chelatase, H subunit; cobaltochelatase, CobN subunit; COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672:IPR011771; KEGG: npu:Npun_F2940 magnesium chelatase subunit H; PFAM: CobN/magnesium chelatase; PRIAM: Magnesium chelatase; SPTR: Magnesium chelatase, H subunit; TIGRFAM: Magnesium-chelatase, subunit H.
  
  
 0.633
chlB
Light-independent protochlorophyllide reductase subunit B; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
  
  
 0.598
Your Current Organism:
Calothrix sp. PCC7507
NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507
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