STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY33245.1PFAM: SNF2 Helicase protein; Helicase conserved C-terminal domain; SNF2 family N-terminal domain; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR000330; KEGG: ana:all7172 hypothetical protein; PFAM: SNF2-related; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: All7172 protein. (1061 aa)    
Predicted Functional Partners:
AFY33246.1
Hypothetical protein; PFAM: SWIM zinc finger; COGs: COG4279 conserved hypothetical protein; InterPro IPR007527; KEGG: ana:all7171 hypothetical protein; SPTR: All7171 protein.
    0.994
AFY35333.1
PFAM: SWIM zinc finger; COGs: COG4279 conserved hypothetical protein; InterPro IPR007527; KEGG: npu:Npun_F3630 zinc finger SWIM domain-containing protein; SPTR: Zinc finger, SWIM domain protein.
    0.978
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 0.922
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.922
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.921
AFY32371.1
DNA polymerase I; PFAM: 3'-5' exonuclease; 5'-3' exonuclease, C-terminal SAM fold; DNA polymerase family A; 5'-3' exonuclease, N-terminal resolvase-like domain; TIGRFAM: DNA polymerase I; COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR018320:IPR020046:IPR020047:IPR002562:IPR 001098:IPR002421:IPR008918; KEGG: ana:alr1254 DNA polymerase I; PFAM: DNA-directed DNA polymerase, family A, palm domain; 5'-3' exonuclease, alpha-helical arch, N-terminal; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; SMART: 5'-3' exonuclease, N-terminal; Helix-hairp [...]
  
 0.885
AFY30516.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.808
AFY33697.1
Sigma 54 interacting domain protein; PFAM: WD domain, G-beta repeat; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001440:IPR019781:IPR019734:IPR001680; KEGG: npu:Npun_F1419 WD-40 repeat-containing protein; PFAM: WD40 repeat, subgroup; Tetratricopeptide TPR-1; SMART: WD40 repeat; Tetratricopeptide repeat; SPTR: WD-40 repeat protein.
  
 0.699
AFY32845.1
ATP-dependent DNA helicase RecQ; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR011545:IPR001650:IPR018982:IPR002121:IPR 014001:IPR006293:IPR004589; KEGG: npu:Npun_R3585 ATP-dependent DNA helicase RecQ; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; SMART: RQC domain; DEAD-like helicase, N-terminal; Helicase, C-terminal; H [...]
 
 
 
 0.668
rpoC2
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
   
  0.655
Your Current Organism:
Calothrix sp. PCC7507
NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507
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