STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY34140.1PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase/QueD family protein; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: npu:Npun_F2811 putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: Putative uncharacterized protein. (290 aa)    
Predicted Functional Partners:
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.979
folE
PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR020602:IPR001474; KEGG: ava:Ava_1949 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1 1; TIGRFAM: GTP cyclohydrolase I.
  
 
 0.960
folE-2
PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR001474:IPR020602; KEGG: ana:alr5287 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1 1; TIGRFAM: GTP cyclohydrolase I.
  
 
 0.960
AFY31353.1
PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: ava:Ava_1455 putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: Putative uncharacterized protein.
  
  
 
0.909
AFY32022.1
PFAM: Alkaline phosphatase; COGs: COG1785 Alkaline phosphatase; InterPro IPR001952:IPR001343; KEGG: cyh:Cyan8802_2010 alkaline phosphatase; PFAM: Alkaline phosphatase; Haemolysin-type calcium-binding repeat; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase.
     
  0.900
queC
preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.853
queF
NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
  
  
 0.768
AFY35821.1
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
  
  
 0.759
AFY36000.1
PFAM: Protein of unknown function (DUF3539); KEGG: naz:Aazo_4424 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.628
AFY31967.1
PFAM: YCII-related domain; COGs: COG2350 conserved hypothetical protein; InterPro IPR005545; KEGG: ava:Ava_2220 YciI-like protein; PFAM: YCII-related; SPTR: YCII-related protein.
  
     0.551
Your Current Organism:
Calothrix sp. PCC7507
NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507
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