STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY35477.1PFAM: FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: bgl:bglu_2p0550 D-amino acid oxidase Aao_1; PFAM: FAD dependent oxidoreductase; PRIAM: D-amino-acid oxidase; SPTR: D-amino acid oxidase Aao_1. (371 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.922
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.914
AFY31039.1
Alanine-glyoxylate aminotransferase apoenzyme; PFAM: Aminotransferase class-V; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: ana:alr1004 alanine--glyoxylate aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Serine--pyruvate transaminase; SPTR: Alanine--glyoxylate aminotransferase.
  
 
 0.913
AFY31260.1
L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
    
 0.903
AFY31508.1
Protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: Cysteine-rich domain; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR001450:IPR004017; KEGG: npu:Npun_F0763 hypothetical protein; PFAM: Cysteine-rich domain; 4Fe-4S binding domain; SPTR: Putative uncharacterized protein.
     
 0.812
AFY31509.1
PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: npu:Npun_F0762 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase, N-terminal; FAD-linked oxidase, C-terminal; SPTR: FAD linked oxidase domain protein.
     
 0.805
AFY33164.1
Glycolate oxidase, subunit GlcD; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR004490:IPR006094:IPR004113; KEGG: npu:Npun_R6128 glycolate oxidase, subunit GlcD; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Glycolate oxidase, subunit GlcD; TIGRFAM: Glycolate oxidase subunit GlcD.
     
 0.805
AFY32886.1
PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase; COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: npu:Npun_F2718 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; PFAM: KDPG/KHG aldolase; PRIAM: 2-dehydro-3-deoxy-phosphogluconate aldolase; SPTR: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: KDPG/KHG aldolase.
     
  0.800
AFY35476.1
Hypothetical protein.
       0.773
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.706
Your Current Organism:
Calothrix sp. PCC7507
NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507
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