STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY35507.1PFAM: NUDIX domain; InterPro IPR000086; KEGG: npu:Npun_F5727 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase. (170 aa)    
Predicted Functional Partners:
nnrD
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
  
 0.946
AFY35602.1
PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR011545:IPR001650:IPR014001; KEGG: npu:Npun_F4515 DEAD/DEAH box helicase domain-containing protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family.
   
 0.628
AFY36283.1
PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR011545:IPR001650:IPR014001; KEGG: ava:Ava_1952 DEAD/DEAH box helicase-like; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: DEAD/DEAH box helicase-like protein; Belongs to the DEAD box helicase family.
   
 0.628
rph
RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 0.623
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
   
 
 0.577
AFY33441.1
PFAM: RNB domain; Ribonuclease B OB domain; TIGRFAM: ribonuclease R; VacB and RNase II family 3'-5' exoribonucleases; COGs: COG0557 Exoribonuclease R; InterProIPR011129:IPR001900:IPR022967:IPR013223:IPR 003029:IPR004476; KEGG: npu:Npun_F6222 VacB/RNase II family 3'-5' exoribonuclease; PFAM: Ribonuclease II/R; Ribonuclease B, N-terminal OB domain; Ribosomal protein S1, RNA-binding domain; SMART: Ribonuclease II/R; Cold shock protein; RNA-binding domain, S1; SPTR: VacB and RNase II family 3'-5' exoribonuclease; TIGRFAM: Ribonuclease II/ribonuclease R, bacteria; Belongs to the RNR ribonuc [...]
   
 0.569
AFY33819.1
Exoribonuclease II; PFAM: RNB domain; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases; COGs: COG0557 Exoribonuclease R; InterPro IPR001900; KEGG: ava:Ava_1322 ribonuclease II; PFAM: Ribonuclease II/R; PRIAM: Exoribonuclease II; SMART: Ribonuclease II/R; SPTR: Ribonuclease II.
   
 0.569
AFY35505.1
Multi-sensor signal transduction multi-kinase; PFAM: Protein kinase domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG3899 ATPase; InterProIPR017442:IPR003018:IPR003594:IPR002290:IPR 020635; KEGG: npu:Npun_R2272 multi-sensor signal transduction multi-kinase; PFAM: ATPase-like, ATP-binding domain; Serine/threonine-protein kinase-like domain; GAF; SMART: ATPase-like, ATP-binding domain; Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain; GAF; SPTR: Multi-sensor signal transduction multi-kinase.
       0.558
AFY35506.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR001789:IPR003661:IPR003594; KEGG: npu:Npun_R2271 response regulator receiver sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; [...]
       0.556
AFY35504.1
Hypothetical protein.
       0.466
Your Current Organism:
Calothrix sp. PCC7507
NCBI taxonomy Id: 99598
Other names: C. sp. PCC 7507, Calothrix sp. PCC 7507
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