node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEV95444.1 | dxr | SAMN05421659_102346 | SAMN05421659_102345 | Regulator of sigma E protease. | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.920 |
SEV95444.1 | ispG | SAMN05421659_102346 | SAMN05421659_102347 | Regulator of sigma E protease. | (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.735 |
SEV95444.1 | polC | SAMN05421659_102346 | SAMN05421659_102348 | Regulator of sigma E protease. | DNA polymerase-3 subunit alpha; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.741 |
SEW09113.1 | dxr | SAMN05421659_104147 | SAMN05421659_102345 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.961 |
SEW09113.1 | dxs | SAMN05421659_104147 | SAMN05421659_12525 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.803 |
SEW09113.1 | ispD | SAMN05421659_104147 | SAMN05421659_112153 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.769 |
SEW09113.1 | ispE | SAMN05421659_104147 | SAMN05421659_10492 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.953 |
SEW09113.1 | ispF | SAMN05421659_104147 | SAMN05421659_103184 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.997 |
SEW09113.1 | ispG | SAMN05421659_104147 | SAMN05421659_102347 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.904 |
SEW09113.1 | ispH | SAMN05421659_104147 | SAMN05421659_108166 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.834 |
SEW28612.1 | dxr | SAMN05421659_108165 | SAMN05421659_102345 | Small subunit ribosomal protein S1/4-hydroxy-3-methylbut-2-enyl diphosphate reductase. | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.400 |
SEW28612.1 | dxs | SAMN05421659_108165 | SAMN05421659_12525 | Small subunit ribosomal protein S1/4-hydroxy-3-methylbut-2-enyl diphosphate reductase. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.413 |
SEW28612.1 | ispE | SAMN05421659_108165 | SAMN05421659_10492 | Small subunit ribosomal protein S1/4-hydroxy-3-methylbut-2-enyl diphosphate reductase. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.469 |
SEW28612.1 | ispF | SAMN05421659_108165 | SAMN05421659_103184 | Small subunit ribosomal protein S1/4-hydroxy-3-methylbut-2-enyl diphosphate reductase. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.410 |
SEW28612.1 | ispG | SAMN05421659_108165 | SAMN05421659_102347 | Small subunit ribosomal protein S1/4-hydroxy-3-methylbut-2-enyl diphosphate reductase. | (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.927 |
SEW28612.1 | ispH | SAMN05421659_108165 | SAMN05421659_108166 | Small subunit ribosomal protein S1/4-hydroxy-3-methylbut-2-enyl diphosphate reductase. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.995 |
dxr | SEV95444.1 | SAMN05421659_102345 | SAMN05421659_102346 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Regulator of sigma E protease. | 0.920 |
dxr | SEW09113.1 | SAMN05421659_102345 | SAMN05421659_104147 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. | 0.961 |
dxr | SEW28612.1 | SAMN05421659_102345 | SAMN05421659_108165 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Small subunit ribosomal protein S1/4-hydroxy-3-methylbut-2-enyl diphosphate reductase. | 0.400 |
dxr | dxs | SAMN05421659_102345 | SAMN05421659_12525 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.990 |