STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEW13846.1Methionine synthase II (cobalamin-independent). (370 aa)    
Predicted Functional Partners:
SEW32630.1
Homocysteine S-methyltransferase.
  
 0.999
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.988
SEW41158.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.969
SEV82701.1
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
 
  
 0.963
SEW36862.1
Homoserine dehydrogenase.
   
 
 0.911
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
 0.895
SEW16237.1
O-acetylhomoserine (thiol)-lyase.
  
 
 0.889
SEW41213.1
O-acetylhomoserine (thiol)-lyase.
  
 
 0.889
SEW18416.1
Methylenetetrahydrofolate reductase (NADPH); Belongs to the methylenetetrahydrofolate reductase family.
  
 0.877
SEW40747.1
Threonine dehydratase.
  
 
 0.861
Your Current Organism:
Clostridium fimetarium
NCBI taxonomy Id: 99656
Other names: CIP 105360, DSM 9179, [. fimetarium, [Clostridium] fimetarium, strain Z-2189
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