STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprF-2Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (358 aa)    
Predicted Functional Partners:
SEW34300.1
PAP2 superfamily protein.
 
     0.873
SEW34311.1
CDP-diacylglycerol---serine O-phosphatidyltransferase.
 
  
 0.833
SEW34315.1
Phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family.
 
   
 0.772
SEW15583.1
Phosphinothricin acetyltransferase.
   
    0.480
SEW34295.1
Hypothetical protein.
       0.467
msrB
Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.422
SEW34290.1
Hypothetical protein.
       0.410
SEW42279.1
ABC-2 type transport system permease protein.
    
  0.403
Your Current Organism:
Clostridium fimetarium
NCBI taxonomy Id: 99656
Other names: CIP 105360, DSM 9179, [. fimetarium, [Clostridium] fimetarium, strain Z-2189
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.