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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PB1_13959COG1290 Cytochrome b subunit of the bc complex. (224 aa)    
Predicted Functional Partners:
PB1_01795
Cytochrome c oxidase subunit 2; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 0.999
PB1_13964
FeS protein subunit; COG0723 Rieske Fe-S protein.
 
 0.999
PB1_13954
Menaquinol-cytochrome c reductase cytochrome b/c subunit; Component of the menaquinol-cytochrome c reductase complex.
 
 0.993
PB1_07662
FAD dependent oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating).
  
 0.985
PB1_01785
COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3.
 
 0.984
nuoH
NADH:ubiquinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
   
 0.984
PB1_08212
COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M).
   
 0.984
PB1_09337
COG2010 Cytochrome c, mono- and diheme variants.
 
 0.984
PB1_15124
COG2010 Cytochrome c, mono- and diheme variants.
 
 0.984
PB1_01790
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 
 0.979
Your Current Organism:
Bacillus methanolicus PB1
NCBI taxonomy Id: 997296
Other names: B. methanolicus PB1, Bacillus methanolicus NCOMB 13113, Bacillus methanolicus str. PB1, Bacillus methanolicus strain PB1
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