STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSOPRP00000000621annotation not available (1291 aa)    
Predicted Functional Partners:
PTPN1
Protein tyrosine phosphatase non-receptor type 1.
    
 0.919
ENSOPRP00000003331
annotation not available
    
 0.919
IGF1
Insulin like growth factor 1.
    
 0.892
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.886
ENSOPRP00000014568
annotation not available
    
 0.886
SH2B2
SH2B adaptor protein 2.
    
 0.868
ENSOPRP00000001741
annotation not available
  
 
0.856
ENSOPRP00000004442
annotation not available
    
 0.836
IRS1
Insulin receptor substrate 1.
    
 0.836
ENSOPRP00000013604
annotation not available
    
 0.836
Your Current Organism:
Ochotona princeps
NCBI taxonomy Id: 9978
Other names: American pika, O. princeps, southern American pika
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.