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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VPS28VPS28 subunit of ESCRT-I. (133 aa)    
Predicted Functional Partners:
TSG101
Tumor susceptibility 101.
   
 0.999
VPS37B
VPS37B subunit of ESCRT-I.
    
 0.994
VPS36
Vacuolar protein sorting 36 homolog.
    
 0.992
VPS25
Vacuolar protein sorting 25 homolog.
   
 0.991
MVB12B
Multivesicular body subunit 12B.
   
 0.990
ENSOPRP00000005821
annotation not available
   
 0.990
UEVLD
UEV and lactate/malate dehyrogenase domains.
   
 0.990
VPS37A
VPS37A subunit of ESCRT-I.
   
 0.970
UBAP1
Ubiquitin associated protein 1.
    
 0.964
VPS37C
VPS37C subunit of ESCRT-I.
    
 0.962
Your Current Organism:
Ochotona princeps
NCBI taxonomy Id: 9978
Other names: American pika, O. princeps, southern American pika
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.