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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STK40Serine/threonine kinase 40. (365 aa)    
Predicted Functional Partners:
ENSOPRP00000009612
annotation not available
    
 
 0.819
TRIB1
Tribbles pseudokinase 1.
    
  
0.813
PRKAG2
Protein kinase AMP-activated non-catalytic subunit gamma 2.
   
 0.784
PRKAG1
Protein kinase AMP-activated non-catalytic subunit gamma 1.
   
 0.784
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
    
 0.779
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
    
 0.779
TRIB3
Tribbles pseudokinase 3.
    
 
0.714
ETV1
ETS variant transcription factor 1.
    
   0.703
ETV5
ETS variant transcription factor 5.
    
   0.703
ENSOPRP00000008651
annotation not available
    
 0.691
Your Current Organism:
Ochotona princeps
NCBI taxonomy Id: 9978
Other names: American pika, O. princeps, southern American pika
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.