close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (665 aa)    
Predicted Functional Partners:
ENSOPRP00000000800
annotation not available
    
 0.999
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
   
 0.999
MNAT1
MNAT1 component of CDK activating kinase.
    
 0.999
GTF2H1
General transcription factor IIH subunit 1.
    
 0.999
GTF2H4
General transcription factor IIH subunit 4.
    
 0.998
GTF2E1
General transcription factor IIE subunit 1.
   
 0.997
ENSOPRP00000012004
annotation not available
    
 0.997
ENSOPRP00000006647
annotation not available
    
 0.996
ENSOPRP00000002011
annotation not available
    
 0.992
GTF2H5
General transcription factor IIH subunit 5.
    
 0.992
Your Current Organism:
Ochotona princeps
NCBI taxonomy Id: 9978
Other names: American pika, O. princeps, southern American pika
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.