close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDN1Endothelin 1. (202 aa)    
Predicted Functional Partners:
EDNRA
Endothelin receptor type A.
    
 0.996
EDNRB
Endothelin receptor type B.
    
 0.996
OXTR
Oxytocin receptor.
    
 0.918
ENSOPRP00000002977
annotation not available
    
 0.905
ENSOPRP00000011291
annotation not available
    
 0.891
ENSOPRP00000012297
annotation not available
    
 0.891
DRD2
Dopamine receptor D2.
    
 0.891
ENSOPRP00000014575
annotation not available
    
 0.891
BDKRB2
Bradykinin receptor B2.
    
 0.889
ADORA1
Adenosine A1 receptor.
    
 0.887
Your Current Organism:
Ochotona princeps
NCBI taxonomy Id: 9978
Other names: American pika, O. princeps, southern American pika
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.