close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRR11Proline rich 11. (352 aa)    
Predicted Functional Partners:
IQGAP3
IQ motif containing GTPase activating protein 3.
   
  0.737
ENSOPRP00000011475
annotation not available
   
   0.644
PTK7
Protein tyrosine kinase 7 (inactive).
    
  0.623
ARID4A
AT-rich interaction domain 4A.
    
 0.616
ARID4B
AT-rich interaction domain 4B.
    
 0.616
FREM1
FRAS1 related extracellular matrix 1.
    
 0.588
MET
MET proto-oncogene, receptor tyrosine kinase.
    
  0.587
MST1R
Macrophage stimulating 1 receptor.
    
  0.587
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
    
 0.587
ENSOPRP00000006285
annotation not available
   
  0.586
Your Current Organism:
Ochotona princeps
NCBI taxonomy Id: 9978
Other names: American pika, O. princeps, southern American pika
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