Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZHX2Zinc fingers and homeoboxes 2. (836 aa)    
Predicted Functional Partners:
ENSOPRP00000015589
annotation not available
   
 0.937
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.903
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 
 0.903
RBSN
Rabenosyn, RAB effector.
  
 
 0.829
TBC1D31
TBC1 domain family member 31.
 
  
 
 0.810
KRAS
KRAS proto-oncogene, GTPase.
    
 0.790
NRAS
NRAS proto-oncogene, GTPase.
    
 0.790
GDI2
GDP dissociation inhibitor 2.
   
 0.785
REM1
RRAD and GEM like GTPase 1.
    
 0.758
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
    
 0.757
Your Current Organism:
Ochotona princeps
NCBI taxonomy Id: 9978
Other names: American pika, O. princeps, southern American pika
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