IRF5 protein (Ochotona princeps) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IRF5

Interferon regulatory factor 5. (493 aa)

Predicted Functional Partners:

TRAF6

0.955

ENSOPRP00000003538

0.838

ENSOPRP00000003559

0.723

SGK3

0.692

ENSOPRP00000004083

0.648

RIPK4

0.648

ENSOPRP00000005776

0.644

STING1

0.633

EP300

0.622

CENPP

0.618

Your Current Organism:

Ochotona princeps

NCBI taxonomy Id: 9978
Other names: American pika, O. princeps, southern American pika

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CENPP	ENSOPRP00000004083	ENSOPRP00000003050	ENSOPRP00000004083	Centromere protein P.	annotation not available	0.637
CENPP	IRF5	ENSOPRP00000003050	ENSOPRP00000005641	Centromere protein P.	Interferon regulatory factor 5.	0.618
CENPP	RIPK4	ENSOPRP00000003050	ENSOPRP00000004523	Centromere protein P.	Receptor interacting serine/threonine kinase 4.	0.401
ENSOPRP00000003538	ENSOPRP00000003559	ENSOPRP00000003538	ENSOPRP00000003559	annotation not available	annotation not available	0.992
ENSOPRP00000003538	IRF5	ENSOPRP00000003538	ENSOPRP00000005641	annotation not available	Interferon regulatory factor 5.	0.838
ENSOPRP00000003559	ENSOPRP00000003538	ENSOPRP00000003559	ENSOPRP00000003538	annotation not available	annotation not available	0.992
ENSOPRP00000003559	IRF5	ENSOPRP00000003559	ENSOPRP00000005641	annotation not available	Interferon regulatory factor 5.	0.723
ENSOPRP00000004083	CENPP	ENSOPRP00000004083	ENSOPRP00000003050	annotation not available	Centromere protein P.	0.637
ENSOPRP00000004083	ENSOPRP00000005776	ENSOPRP00000004083	ENSOPRP00000005776	annotation not available	annotation not available	0.606
ENSOPRP00000004083	EP300	ENSOPRP00000004083	ENSOPRP00000011216	annotation not available	E1A binding protein p300.	0.571
ENSOPRP00000004083	IRF5	ENSOPRP00000004083	ENSOPRP00000005641	annotation not available	Interferon regulatory factor 5.	0.648
ENSOPRP00000005776	ENSOPRP00000004083	ENSOPRP00000005776	ENSOPRP00000004083	annotation not available	annotation not available	0.606
ENSOPRP00000005776	EP300	ENSOPRP00000005776	ENSOPRP00000011216	annotation not available	E1A binding protein p300.	0.996
ENSOPRP00000005776	IRF5	ENSOPRP00000005776	ENSOPRP00000005641	annotation not available	Interferon regulatory factor 5.	0.644
ENSOPRP00000005776	RIPK4	ENSOPRP00000005776	ENSOPRP00000004523	annotation not available	Receptor interacting serine/threonine kinase 4.	0.401
EP300	ENSOPRP00000004083	ENSOPRP00000011216	ENSOPRP00000004083	E1A binding protein p300.	annotation not available	0.571
EP300	ENSOPRP00000005776	ENSOPRP00000011216	ENSOPRP00000005776	E1A binding protein p300.	annotation not available	0.996
EP300	IRF5	ENSOPRP00000011216	ENSOPRP00000005641	E1A binding protein p300.	Interferon regulatory factor 5.	0.622
EP300	RIPK4	ENSOPRP00000011216	ENSOPRP00000004523	E1A binding protein p300.	Receptor interacting serine/threonine kinase 4.	0.401
IRF5	CENPP	ENSOPRP00000005641	ENSOPRP00000003050	Interferon regulatory factor 5.	Centromere protein P.	0.618