Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRLProlactin. (227 aa)    
Predicted Functional Partners:
PRLR
Prolactin receptor.
    
 0.999
ENSSDAP00000010227
annotation not available
   
 0.985
LEPR
Leptin receptor.
     
 0.980
GHR
Growth hormone receptor.
     
 0.978
JAK2
Janus kinase 2.
     
 0.977
LEP
Leptin.
     
 0.974
CRLF1
Cytokine receptor like factor 1.
    
 0.965
IFNAR1
Interferon alpha and beta receptor subunit 1.
  
  
  0.947
POU1F1
POU class 1 homeobox 1.
   
 
 0.945
JAK3
Janus kinase 3.
     
 0.943
Your Current Organism:
Spermophilus dauricus
NCBI taxonomy Id: 99837
Other names: Citellus dauricus, Daurian ground squirrel, S. dauricus
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