Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma. (1074 aa)    
Predicted Functional Partners:
PIK3R5
Phosphoinositide-3-kinase regulatory subunit 5.
   
 0.999
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.997
AKT1
AKT serine/threonine kinase 1.
    
 0.995
LYN
LYN proto-oncogene, Src family tyrosine kinase.
    
 0.993
PDPK1
3-phosphoinositide dependent protein kinase 1.
    
 0.993
ENSSDAP00000011017
annotation not available
    
 0.992
ENSSDAP00000003068
annotation not available
    
 0.991
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
0.989
IRS1
Insulin receptor substrate 1.
    
 0.989
YES1
YES proto-oncogene 1, Src family tyrosine kinase.
    
 0.986
Your Current Organism:
Spermophilus dauricus
NCBI taxonomy Id: 99837
Other names: Citellus dauricus, Daurian ground squirrel, S. dauricus
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